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Chiral Separations: Methods and Protocols focuses on chromatographic and electroseparation techniques for chiral separation on an analytical scale. It is not the aim of this book to give a comprehensive overview of all applications of chiral separation principles. Because there are several thousand publications on this topic, this would require a series of books. For comprehensive overviews the reader is referred to specialized review articles. Chiral Separations: Methods and Protocols begins with an introduction to the different techniques, principles, and mechanisms of chiral separation, and includes a historical background (Chapter 1). Chapters 2–4 review some special techniques and include practical advice for users. The remainder of the book is devoted to articles describing typical procedures for enantiomer separation by chromatographic and electromigration techniques applying different chiral separation principles. These procedures may be of general character, or are otherwise presented by means of applications to substance classes or special compounds. These chapters differ from conventional articles, because primary emphasis is set on giving reliable procedures for users. Special attention is given to important experimental data, and practical hints in the “Notes” section enable the reader to adapt these procedures to one’s separation problems. Forty-three authors from twenty-four research laboratories all over the world have contributed to Chiral Separations: Methods and Protocols.This book should be helpful to biochemists, pharmaceutical chemists, clinical chemists, molecular biologists, and pharmacologists, both in research institutions and in industry.