Tidak ada kategori

Bioinformatics is a multidisciplinary field, which encompasses molecular biology, biochemistry and genetics on the one hand, and computer science on the other. Bioinformatics are methods from various areas of computer science, such as alogoritms, combinatorial optimization, integer linear programming, constraint programming formal language theory, neural nets, machine learning, motif recognation, inductive logic programming database systems, knowledge discovery and database mining. The fusion on biomedicine and computer technology offers substantial benefits to all scientists involved in biomedical research in support of their general mission of improving the quality of health by increasing biological knowledge. Basically, there are two ways of structuring the field of bioinformatics. One is intrinsically by the type of problem that is under consideration. The second is extrinsically, by the application scenario in which bioinformatics operates and by the type of molecular biology experiment that it supports. The intrinsic view is the subject of Part 1: it structures bioinformatics in methodical layers. Lower layer operate directly on the genomic text that is the result of sequencing projects. Higher layers operate on higher level information derived from this text. Part 1 discusses sub problems of bioinformatics that provide components in a global bioinformatics. The extrinsic view is the focus of the second Part: chapters concentrate on several important application scenarios that can only be supported effectively by combning components discussed in Part 1.